Quantum computers cannot calculate atomic energy nor discover drugs.

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Quantum computer is useless
Quantum computer cannot calculate molecules or proteins
Quantum phase estimation is useless

Impractical quantum computers unable to calculate anything rely on overhyped hybrid VQE method that uses classical computers for calculating all atomic energies by useless quantum variational methods that cannot predict anything.

(Fig.1)  The recent overhyped research "Hybrid quantum computing for drug discovery" is fake, using only 2 useless qubits (= one qubit can take only 0 or 1 values ) and impractical quantum mechanics that cannot predict any molecules nor drugs.

Quantum mechanics cannot solve its Schrödinger equation nor predict any multi-electron atomic energies.

Quantum mechanics with unreal parallel worlds cannot solve its Schrödinger equations nor predict any multi-electron atomic energies ( this or this-p.21 ), much less predict technologies.

Physicists have to artificially choose fake trial wavefunctions for unsolvable Schrodinger equation in the impractical approximate quantum mechanical variational methods that cannot predict anything.

For the unsolvable Schrodinger equations, physicists have to artificially choose fake trial wavefunctions (= basis sets ) expressed as unphysical antisymmetric wavefunctions and integrate them (= instead of solving them ) with the unsolvable Schrodinger energy equation (= Hamiltonian H = total energy ) to get the fake average total energy in quantum mechanical approximate variational methods ( this or this-p.1~p.20 ).

This quantum mechanical approximate variational methods such as Hartree-Fock and impractical configuration interaction (= CI ) are too time-consuming, impractical, cannot predict anything ( this or this-p.10-lower,  this or this-p.6-2.2~p.7 ).

Because they have to try infinite possible (fake) trial wavefunctions with infinite terms and infinite free parameters ( this or this-4~5th-paragraphs ) to find ones giving the lowest total energy in this impractical quantum variational methods that take infinite time ( this or this-p.6-4.4.1 ).

Neither the unsolvable Schrodinger equation nor quantum mechanical approximate variational methods can predict true atomic energies.

↑ This quantum mechanical variational methods are said to give only upper bound energy, cannot predict exact atomic lowest ground-state energies themselves (= actually this variational method is wrong, can give wrong energies lower than the true atomic lowest energies ).

This or this-p.4-1st-paragraph says  -- No quantum mechanical prediction
"So we do not have any way of knowing how good or how bad our trial wave function is. The variational method also does Not tell us what kind of a trial function we must choose ( this or this-(9.80),  this or this-p.3-lower )"

This or this-p.2~p.3 say  -- Useless variational methods
"we cannot solve the problem exactly (= Schrodinger equations are unsolvable )"
"The variational principle... Problem: you do NOT know how close your result is compared to the exact result ( this-p.7-5-caveat )"

No matter what trial wavefunctions are chosen, they can never be true solutions of the unsolvable multi-electron Schrödinger equations, which fact disproves quantum mechanics.

In hybrid variational quantum eigensolver (= VQE ) methods, classical computers have to perform all atomic energy calculations instead of the useless quantum computers.

Overhyped quantum computers are impractical forever, cannot get right answers or factor even 21 due to a lot of errors which cannot be corrected.

So to seemingly calculate atomic energy, physicists must rely on deceptive hybrid methods such as variational quantum eigensolver (= VQE ) where classical computers must perform all energy calculations instead of the useless error-prone quantum computers ( this or this-middle-The VQE algorithm: ).

Classical computers (= instead of useless quantum computer ) have to calculate and find the lowest atomic energy from artificially-chosen fake trial wavefunctions (= ansatz ) in impractical quantum variational method or VQE that cannot predict anything.

This hybrid quantum variational eigensolver (= VQE ) is based on the impractical quantum variational methods that just choose fake trial wavefunctions called ansatz ( this or this-Implementation,  this or this-Key concepts in VQE-#ansatz ).

↑ Dependence on what trial wavefunctions (= ansatz ) are chosen for unsolvable Schrodinger equations means hybrid quantum methods = VQE also cannot predict any multi-electron atomic energies ( this-p.1-abstract ).

From these artificially-chosen trial wavefunctions (= ansatz ) with free parameters, classical computers adjust the free parameters to find the lowest ground-state energy within the chosen trial wavefunctions in this VQE.

↑ So today's error-prone quantum computers are completely useless, can do nothing even in this deceptive hybrid quantum-classical methods.

Results of hybrid quantum computing methods such as VQE depend on choice of fake trial wavefunctions (= VQE ), which cannot predict anything nor new drugs.

This or this or this-VQE choosing trial wavefunctions or ansatz ↓

3rd-paragraph says  -- VQE chooses ansatz
"VQE works by preparing a trial quantum state using a parametrized quantum circuit (an ansatz ), measuring the expectation value of the Hamiltonian, and then using a classical optimizer to iteratively adjust the circuit parameters until the energy is minimized."

lower-What is the the role of the ansatz in VQE? says
"The choice of ansatz (= trial wavefunctions, this-p.1-right-2nd-paragraph ) is critical to VQE's performance. It determines which quantum states the algorithm can explore"

↑ Quantum mechanics and (impractical) hybrid quantum VQE (= heavily relying on classical computers ) depend on choice of (fake) trial wavefunctions (= ansatz ), which cannot predict anything nor new drugs ( this or this-lower-Key takeaways,  this-p.4-2nd-last-paragraph ).

VQE prepares fake simplified useless atomic (Hamiltonian) energy equation for the error-prone quantum computers ( only for show ).  Classical computers must calculate and optimize atomic energy from chosen trial wavefunctions (= ansatz ).

VQE prepares the fictitious simplified Hamiltonian (= total ) energy H expressed by small numbers of quantum bits or qubits, which is called mapping.  ← This fake simplified atomic energy equation often uses only two qubits 01 = one qubit takes only 0 or 1 values = still Not a quantum computer, which cannot calculate atomic energy nor drug discovery contrary to hypes ( this or this-lower-Implications and limitations,  this or this-p.15-1. ).

↑ And this fake simplified quantum computer version's Hamiltonian H (= total ) energy's coefficient parameters h (= integral of chosen trial wavefunctions by incorrect Hartree-Fock methods ) must be computed by a classical computer ( this-p.6-lower~p.7,  this or this-p.4-(2),  this or this-p.13-(88) ) Not by the useless quantum computers.

↑ Then, they flip (= measure ) the qubits (= only a few qubits, Not a quantum computer ) based on energy parameters (= θ ) adjusted or optimized by classical computers in this VQE.

Classical computers have to calculate and find the lowest atomic energy in the original Hamiltonian energy equation by adjusting parameters of the chosen trial wavefunctions in this VQE, so quantum computers are unnecessary.

Quantum computers, which are used only to measure qubits controlled by a classical computer for show, are unnecessary in VQE.

This or this-p.2-left-4th-paragraph says  -- Quantum computer unneeded
"an ansatz (= chosen trial wavefunction ) with several tunable parameters is constructed, and a quantum circuit capable of producing this ansatz is designed. The ansatz parameters are variationally adjusted until they minimize the expectation value of the molecular Hamiltonian. Classical hardware is used to precompute all the Hamiltonian terms and to update the parameters during the circuit optimization. The quantum hardware is only used to prepare a state (defined by its current set of ansatz parameter values) and to perform measurements of the various interaction terms in the (simplified fake) molecular Hamiltonian"

↑ So the impractical error-prone quantum computers are unnecessary and used only to measure qubits (= expressing the simplified fake version of atomic energy equation ) controlled by classical computers that must calculate and find the lowest atomic energy by adjusting parameters of the artificially-chosen trial wavefunctions in the quantum variational methods that cannot predict anything.

Quantum computers can never calculate useful atomic energy nor discover drugs even in their deceptive hybrid VQE methods.

This or this-site on hopeless quantum computers (2026) ↓

3rd-paragraph says  -- Useless quantum computer
"even the most popular quantum algorithms face serious obstacles when trying to compute the lowest energy state of molecules"

9th-paragraph says  -- Classical computer needed
"VQE works through a hybrid approach where a quantum computer prepares a candidate quantum state for the molecule, while a classical computer adjusts parameters step by step to minimize the calculated energy. The idea is to gradually approach the molecule's true ground state."

11th-paragraph says  -- Impractical VQE
"For instance, when the researchers examined the chromium dimer molecule (Cr₂), they found that just one iteration of the VQE calculation could take about 25 days. When the many required optimization steps are included, the total runtime could stretch to around 24 years ( this-p.3-left-1st-paragraph )."

Overhyped AI, machine-learning are used only to help classical computers adjust parameters based on previous data for chosen fake trial wavefunctions that cannot predict anything.

Overhyped AI, machine-learning are used only to help classical computers find parameters based on the previously-obtained data for the artificially-chosen trial wavefunctions which cannot predict anything.

The recent overhyped quantum computer drug discovery research used only 2 useless qubits (= one qubit takes only 0 or 1 value, still Not a quantum computers ) in hybrid VQE, which cannot calculate anything.

This or this news on fake quantum computers for drug discovery ↓

11th-paragraph says  -- Simulate drug interaction ?
"the anticancer drug sotorasib, a KRAS inhibitor targeting a specific KRAS gene mutation, G12C. Prior research has implicated the KRAS gene mutation in many cancers and has shown itself to be notoriously difficult to treat. Effective inhibition of this mutation could lead to significant advancements in the treatment of various aggressive cancers. In the study, the team used a hybrid computing method, starting with a quantum emulator before moving to a quantum computer, to simulate the drug’s interaction with its target."

3rd-last-paragraph says  -- Impractical quantum computer
"Despite its promising report, using quantum computers for current drug discovery faces significant limitations. For example, quantum computing is still plagued by longer computational times and errors, which impede its accuracy and efficiency in drug discovery"

Fake quantum computer drug discovery research used only 2 useless qubits (= Not a quantum computer ) for only the chosen 2 electrons' orbitals inside a drug molecule whose energy must be calculated by a classical computer from chosen fake trial wavefunctions in VQE that cannot predict anything nor discover drugs.

↑ This or this fake quantum computer drug discovery research ↓

p.3-3rd-last-paragraph says
"In this work, we study the prodrug design for β-lapachone, a natural product with extensive anticancer activity"

p.3-2nd-last-paragaph says   Only 2 orbits (= 2 electrons ) calculated
"In this work, we employed the active space approximation,,, which simplifies the QM region into a more manageable two electron/two orbital system (= only chosen 2 electrons' orbitals inside some molecule were calculated by quantum mechanics as active space ).... the results by quantum computers are expected to be consistent with the CASCI energy (= approximate CI )...."

p.3-2nd-last-paragaph says  -- Using only 2 useless qubits
"..The wave function of the active space (= only these artificially selected active space orbits are calculated for rough approximation, Not quantum mechanical prediction, this or this-3rd-paragraph,  this-p.2-last-paragraph~p.3 ) can then be represented by a 2-qubit superconducting quantum device... quantum circuit for VQE"  ← Only 2 orbits of the molecules are selected as active space (= targets for calculations, so Not quantum mechanical prediction,  this or this-p.16,p.33 ) for 2 qubits (= taking only 01 values )

p.6-1st-paragraph says  -- Only 2 qubits, Not quantum computer
"the active space wavefunction is processed using 2 qubits."  ← Only 2 orbits within the prodrug molecule were selected for the useless quantum computer's just 2 qubits (= one qubit takes only 0 or 1 value, so still Not a quantum computer, ) as the active space (= selected as targets for calculation, this-p.2 ), so this research did Not compute all the atomic orbitals related to the drug molecule at all, contrary to hypes.

p.9-Methods say  -- Classical computer optimizes parameters
"The VQE algorithm uses a parameterized quantum circuit (PQC).. to construct a quantum state that approximates the ground state of the system. The parameters of the quantum circuit θ are optimized to its optimal value θ* using a classical ( computer ) optimization algorithm,.. According to the Rayleigh-Ritz variational principle,"

p.10-4th-paragraph says  -- No quantum mechanical prediction
" Te frozen core provides an effective repulsion potential"  ← Most atomic orbitals were approximately or inaccurately treated as effective (pseudo-)potential energy without quantum mechanical prediction ( this or this-p.1 ).

For unsolvable Schrodinger equations, quantum mechanical approximate variational methods must artificially choose fake trial wavefunctions only for the chosen active space orbitals (= due to taking too much time ), which cannot predict anything.

This-p.1-abstract says  -- Choose orbits, Not prediction
"One of the key challenges of quantum-chemical multi-configuration methods is the necessity to manually select orbitals for the active space. This selection requires both expertise and experience and can therefore impose severe limitations on the applicability of this most general class of ab initio methods. A poor choice of the active orbital space may yield even qualitatively wrong results."

↑ So the calculation results are changed depending on which orbitals are chosen as active space (= other orbits in non-active space were roughly and incorrectly calculated ), which is Not quantum mechanical prediction ( this-p.2-5th-paragraph,  this or this-p.16,p.33 ).

As a result, both quantum mechanics and quantum computers are useless and unable to predict any atomic energies, much less discover drugs.