Medical research is deadend due to useless electron microscopes that cannot clarify atomic mechanism of diseases.

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Bad microscopes.

The current best microscope (= cryogenic-electron microscopy = cryo-EM ) is useless, unable to get atomic resolution, which hampers medicine curing diseases.

(Fig.1)  Medical research cannot clarify atomic mechanism nor cure diseases due to bad electron microscopes that cannot see atoms.

Medical research is deadend, unable to cure cancers, Alzheimer, because the current best microscope = cryo-electron microscopy has been useless, cannot clarify atomic mechanisms of proteins since 1970.

The present medical research (and hyped AI ) has been deadend with No progress (= still No cures for cancers or Alzheimer ).

Because the best mainstream method for clarifying molecular mechanisms in medical research has been (useless) hyped cryo-electron microscope (= cryo-EM ), which can Not clarify atomic mechanism due to its bad resolution ( this-limitations of cryo EM ), since 1970 (= No progress for long years, this-history ).

Only multi-probe atomic force microscopes can clarify atomic mechanisms and cure diseases.

Only multi-probe atomic force microscopes (= newer than the old electron microscopy ) can directly see and clarify atomic mechanism of proteins for curing diseases, which has been hampered by the unreal quantum mechanical atomic model for a long time.

Even the latest research uses the useless cryo-electron microscope that cannot see nor clarify atomic mechanisms of proteins.

The 2nd, 3rd paragraphs of this hyped news (8/21/2025) say
"a team of researchers.. has succeeded in establishing the first comprehensive transport model of the plasma membrane Ca2+-ATPase (PMCA) by resolving its 3D structure"  ← fake news

"This mechanism could be a promising (= still useless ) starting point for developing new drugs"

Cryo-electron microscope is too bad resolution (> 3Å ) that cannot clarify atomic structures, which need 1Å resolution.

This research paper ↓

p.2-left-2nd-paragraph says "we determined an ensemble of PMCA2 (= plasma membrane Ca2+-ATPase ) structures.. by cryo-electron microscopy (cryo-EM)"

p.2-right-2nd-paragraph says
"The eight resulting structures of PMCA2 had an overall resolution ranging from 2.8 Å to 3.6 Å.  ← Cryo-electron microscopes are useless, unable to get atomic resolution of less than (= each atomic size is less than 1 angstrom or 1Å,  this-middle-picture's cryo-EM's resolution is worse than the atomic 1Å = 1 Angstrom resolution )

p.13-right-1st-paragraph says "Because the local resolution of Ig1 was still too low to allow for de novo modelling"

p.25-even this latest Cryo-EM's (map) resolution was too bad (= 6.3Å, 9.5Å, this-p.3-p.6-local resolution ), which cannot clarify atomic mechanism (of proteins or diseases ) needing less than 1Å resolution, so cannot cure cancers or Alzheimer.

 

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